Dermacyte

Dermacyte : (dehydrated Human Amniotic Membrane (dHAM)
Dehydrated Amniotic allograft membrane is a novel human placental based tissue product employed in healing of unresolved wounds. Dermacyte (dHAM) is easy to handle and stable at room temperature. Key components includes ECM extra cellular matrix], growth factors and cytokines.

Human amniotic membrane (HAM): is the innermost layer of placenta employed in healing of unresolved wounds obtained from labour during the time of delivery.

Medical applications of Dermacyte (dehydrated Human Amniotic Membrane (dHAM)
Is in the field of surgical ophthalmology and has been extended to wounds of other areas including diabetic neurovascular ulcers, venous stasis ulcers, postoperative or posttraumatic chronic wounds, and post-surgical wound dehiscence. Other potential uses include reparative membrane in orthopaedics, neurosurgery, periodontology OB/GYN, general and reconstructive surgery.

Salient features
 Provides a matrix for cellular migration and proliferation.
 Promotes enhanced healing of the wound.
 Is non-immunogenic.
 Reduces scar tissue.
 Has antibacterial properties.
 Reduces pain at site of application.
 Provides a natural biological barrier.
 Contains a number of essential growth factors and cytokines

Indications for use
Is intended for use in wounds. This placental derived allograft tissue is intended for homologous use for the repair, reconstruction and replacement of skin at the discretion of a physician.

 Clinical applications to Repair, Reconstruct, and Replace for:
 Chronic and acute wounds.
 Diabetic ulcers.
 Venous and Arterial ulcers.
 Pressure ulcers
 Traumatic injuries
 Burns
 Surgical wounds

FDA Regulation
Dermacyte (dehydrated Human Amniotic Membrane) is regulated as a Human cellular and Tissue-based product [HCT/P] UNDER SECTION 361 and the public health service act and is governed by the FDA Centre for Biologics Evaluation and Research [CBER]

Precautions
 Wound should be free of exudate before the dehydrated amniotic membrane allograft is administered.
 Should not be administered to the patients who are hypersensitive to ethanol.

Storage conditions
To be stored at ambient temperatur

Shelf life
5 Years.

Conclusion
Dermacyte (dehydrated Human Amniotic Membrane) is uniquely suited material for use as an allograft in wound management, used in natural form then in preserved preparations. The material aids in healing process through a number of physical, biochemical and molecular biological pathways to promote healing while simultaneously reducing the inflammation and scar formation. Wounds respond to best advanced therapies such as dehydrated Human amniotic membrane.