Cellex – a completely connected, inline device which requires only 90 minutes for a whole treatment as against the 240 to 270 minutes required by other machines…
THERAKOS® CELLEX® Photopheresis System
Therakos Cellex delivers a fully integrated, automated extracorporeal photopheresis (ECP) system, providing superior efficiency, safety, and patient outcomes.
Key advantages:
- Faster treatment times*1:
- Single-needle mode: 105 mins/Treatment
- Double-needle mode: 75 mins/Treatment
- Only Online, integrated device to be approved by both FDA and EU certified.
- Workday Limitation: Based on a 7.5-hour workday (450 minutes)*2, integrated systems triple patient throughput, maximizing efficiency and bed utilization in clinical settings.
- compact and integrated system that enhances mobility.
- Single machine performs cell collection, ECP treatment and reinfusion of treated blood back to the patient, thus reducing the hidden cost.
1. Data on file. Ref-01420. Mallinckrodt Pharmaceuticals
2. Azar N, Leblond V, Ouzegdouh M, Button P. A transition from using multi-step procedures to a fully integrated system for performing extracorporeal photopheresis: A comparison of costs and efficiencies. J Clin Apher. 6 2017 Dec;32(6):474-478. doi: 10.1002/jca.21542. Epub 2017 Apr 17. PMID: 28419561; PMCID: PMC5724655
How the THERAKOS CELLEX System Works:
- Blood Collection: The patient’s blood is drawn, and the white blood cells (including T cells) are separated from the rest of the blood using centrifugation.
- Photoactivation:
- A photosensitizing agent, such as 8-methoxypsoralen (8-MOP), is introduced. This agent makes T cells sensitive to ultraviolet A (UVA) light.
- The separated white blood cells are then exposed to UVA light, which damages the DNA of the treated cells, rendering them apoptotic (programmed cell death).
- Reinfusion: The treated white blood cells are reinfused back into the patient, where they induce an immunomodulatory effect by stimulating regulatory T cells (Tregs) and reducing inflammation or abnormal immune responses.