Cellex – a completely connected, inline device which requires only 90 minutes for a whole treatment as against the 240 to 270 minutes required by other machines.
THERAKOS® CELLEX® Photopheresis System
THERAKOS® CELLEX® delivers a fully integrated, automated extracorporeal photopheresis (ECP) system, providing superior efficiency, safety, and patient outcomes.
Key advantages:
- Faster treatment times(1):
- Single-needle mode: 105 mins/Treatment
- Double-needle mode: 75 mins/Treatment
- Only Online, integrated device to be approved by both FDA and EU certified.
- Workday Limitation: Based on a 7.5-hour workday (450 minutes)(2), integrated systems triple patient throughput, maximizing efficiency and bed utilization in clinical settings.
- Compact and integrated system that enhances mobility.
- Single machine performs cell collection, ECP treatment and reinfusion of treated blood back to the patient, thus reducing the hidden cost.
- Data on file. Ref-01420. Mallinckrodt Pharmaceuticals.
- Azar N, Leblond V, Ouzegdouh M, Button P. A transition from using multi-step procedures to a fully integrated system for performing extracorporeal photopheresis: A comparison of costs and efficiencies. J Clin Apher. 6 2017 Dec;32(6):474-478. doi: 10.1002/jca.21542. Epub 2017 Apr 17. PMID: 28419561; PMCID: PMC5724655
Value Proposition
100
Reduced Hospital Stays
500
Improved Transplant Outcomes
4200
Smiling Customer
How the THERAKOS® CELLEX® System Works:
- Blood Collection:
- The patient’s blood is drawn, and the white blood cells (including T cells) are separated from the rest of the blood using centrifugation.
- Photoactivation:
- A photosensitizing agent, such as 8-methoxypsoralen (8-MOP), is introduced. This agent makes T cells sensitive to ultraviolet A (UVA) light.
- The separated white blood cells are then exposed to UVA light, which damages the DNA of the treated cells, rendering them apoptotic (programmed cell death).
- Reinfusion:
- The treated white blood cells are reinfused back into the patient, where they induce an immunomodulatory effect by stimulating regulatory T cells (Tregs) and reducing inflammation or abnormal immune responses.
With faster treatment times, continuous operation, and advanced customization, Cellex reduces manual errors, increases patient throughput, and ensures precision for personalized care setting the standard for modern photopheresis systems.
